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Article

Cross-subtype T-cell immune responses induced by a human immunodeficiency virus type 1 group m consensus env immunogen.

Journal of virology - 1 Jul 2006

Weaver Eric A, Lu Zhongjing, Camacho Zenaido T, Moukdar Fatiha, Liao Hua-Xin, Ma Ben-Jiang, Muldoon Mark, Theiler James, Nabel Gary J, Letvin Norman L, Korber Bette T, Hahn Beatrice H, Haynes Barton F, Gao Feng

Abstract excerpt

The genetic diversity among globally circulating human immunodeficiency virus type 1 (HIV-1) strains is a serious challenge for HIV-1 vaccine design. We have generated a synthetic group M consensus env gene (CON6) for induction of cross-subtype immune responses and report here a comparative study of T-cell responses to this and natural strain env immunogens in a murine model. Three different strains of mice were...

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Identifiers

PMID: 16809280
DOI: 10.1128/JVI.02484-05
PMCID: PMC1489064

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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