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Article

Cross-clade CD8(+) T-cell responses with a preference for the predominant circulating clade.

Journal of acquired immune deficiency syndromes (1999) - 1 Nov 2005

McKinnon Lyle R, Ball T Blake, Kimani Joshua, Wachihi Charles, Matu Lucy, Luo Ma, Embree Joanne, Fowke Keith R, Plummer Francis A

Abstract excerpt

Human immunodeficiency virus (HIV) genetic diversity is a major impediment to the design of a successful vaccine. Even if an HIV vaccine is proven effective, it remains to be seen whether this protection will extend to inter-clade, intra-clade, and recombinant strains. We used recombinant vaccinia-based interferon gamma (IFN) Elispot assays to test the inter-clade crossreactivity of clades A, B, C, and D HIV Env...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16249696
DOI: 10.1097/01.qai.0000184858.16447.04

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