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Article

HIV-specific T cells: strategies for fighting a moving target.

Current HIV research - 1 Dec 2010

McKinnon Lyle R, Kaul Rupert, Herman Melissa, Plummer Francis A, Ball T Blake

Abstract excerpt

HIV vaccine development faces many hurdles, including the failure of empirical approaches, an incomplete understanding of protective immunity, and the extreme genetic diversity of HIV-1. HIV is a moving target in at least two key ways: 1) within an infected individual, years of evolution lead to the formation of quasispecies, and selection of variants with increased fitness, and 2) during the course of the...

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Identifiers

PMID: 21054251
DOI: 10.2174/157016210794088245

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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