A simple nonradioactive method of DNA typing for subsets of HLA-DR4: prevalence data on HLA-DR4 subsets in three diabetic population groups.

doi:10.1016/0198-8859(91)90096-r

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

A simple nonradioactive method of DNA typing for subsets of HLA-DR4: prevalence data on HLA-DR4 subsets in three diabetic population groups.

Human immunology - 1 Aug 1991

Ju L Y, Gu X F, Bardie R, Krishnamoorthy R, Charron D

Abstract excerpt

The molecular basis of eight DR4 subtypes resides in several nucleotide substitutions in the third hypervariable region of the DR beta 1 chain. The typing of DR4 subsets using the mixed lymphocyte culture (MLC) assay or allele-specific oligonucleotide hybridization is expensive, cumbersome, and r...

Topics

Alleles
Base Sequence
China
DNA
Diabetes Mellitus, Type 1
Electrophoresis, Polyacrylamide Gel
Genotype
HLA-DR Antigens
HLA-DR4 Antigen
HLA-DRB1 Chains
Histocompatibility Antigens Class II
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Methods

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Restriction Fragment Length

Prevalence

Tunisia

Source

Open in PubMed

Identifiers

PMID: 1680838
DOI: 10.1016/0198-8859(91)90096-r

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1680838-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A simple nonradioactive method of DNA typing for subsets of HLA-DR4: prevalence data on HLA-DR4 subsets in three diabetic population groups.PMID 1680838Read ↗

HLA-DRB1*04 high resolution typing.Semantic proximity Read ↗

DNA typing for class II HLA antigens with allele-specific or group-specific amplification. I. Typing for subsets of HLA-DR4.Semantic proximity Read ↗

Heterogeneity of HLA-DRB1*04 and its associated haplotypes in the North Indian population.Semantic proximity Read ↗

Allelic typing of the HLA-DR4 group by polymerase chain reaction--single-strand conformation polymorphism analysis.Semantic proximity Read ↗

Comparison of two HLA-DRB high resolution microtiter plate reverse hybridization typing methods: advantage of a codon-86 valine or glycine PCR segregation.Semantic proximity Read ↗

High resolution genetic typing of the class II HLA-DRB1 locus using group-specific amplification and SSO-hybridisation in microplates.Semantic proximity Read ↗

HLA-DRB4 genotyping by PCR-RFLP: diversity in the associations between HLA-DRB4 and DRB1 alleles.Semantic proximity Read ↗

Multiplex ARMS-RFLP: a simple and rapid method for HLA-DR4 subtyping.Semantic proximity Read ↗

An HLA-DR typing protocol using group-specific PCR-amplification followed by restriction enzyme digests.Semantic proximity Read ↗

Multiplex ARMS-PCR-RFLP method for high-resolution typing of HLA-DRB1.Semantic proximity Read ↗

A simple and economical DRB1 typing procedure combining group-specific amplification, DNA heteroduplex and enzyme restriction analysis.Semantic proximity Read ↗

Population and family studies of HLA-DR4 by use of oligonucleotide typing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.