DNA typing for class II HLA antigens with allele-specific or group-specific amplification. I. Typing for subsets of HLA-DR4.

doi:10.1016/0198-8859(90)90094-6

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Article

DNA typing for class II HLA antigens with allele-specific or group-specific amplification. I. Typing for subsets of HLA-DR4.

Human immunology - 1 Jan 1990

Gao X J, Fernandez-Vina M, Shumway W, Stastny P

Abstract excerpt

DNA sequences that distinguish the subsets of HLA-DR4 are also found on several other alleles. This makes typing of heterozygotes with oligonucleotide probes quite impractical. We have therefore developed a procedure in which, in a first step, DNA of the genes to be analyzed is amplified selectiv...

Topics

Alleles
Base Sequence
DNA Probes
Gene Amplification
Gene Frequency
HLA-DR4 Antigen
Humans
Molecular Sequence Data
Polymerase Chain Reaction

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