Article
Heterogeneity of HLA-DRB1*04 and its associated haplotypes in the North Indian population.
Human immunology - 1 Jan 2002
Jaini Ritika, Kaur Gurvinder, Mehra Narinder K
Abstract excerpt
HLA-DR4 has been implicated in several diseases including rheumatoid arthritis (RA) and type I diabetes, the strength of associations being ethnically variable. Unusually high level of heterogeneity in DR4-DQB1 haplotypes has been reported in the Indian population. The present study is an attempt to determine the genetic diversity of the HLA-DR4 allelic family and its associated DQA1-DQBI haplotypic combinations...
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