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Article

Genetic polymorphisms in the angiotensin II receptor gene and their association with open-angle glaucoma in a Japanese population.

Investigative ophthalmology & visual science - 1 Jun 2005

Hashizume Kouhei, Mashima Yukihiko, Fumayama Tomoyo, Ohtake Yuichiro, Kimura Itaru, Yoshida Kazuhide, Ishikawa Karin, Yasuda Noriko, Fujimaki Takuro, Asaoka Ryo, Koga Takahisa, Kanamoto Takashi, Fukuchi Takeo, Miyaki Koichi

Abstract excerpt

PURPOSE: The local renin-angiotensin system (RAS) is present in the ciliary body and plays a role in regulating aqueous humor dynamics and thus intraocular pressure (IOP). The purpose of this study was to determine whether gene polymorphisms in the RAS increase the risk of development of glaucoma in the Japanese. METHODS: A case-control study was performed in 698 Japanese subjects: 190 patients with primary...

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Share to Angiotensin II Type 1 Receptor Blockers
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15914614
DOI: 10.1167/iovs.04-1100

Genes

AGTR2
AGTR1
ACE
AGT
REN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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