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Article

Intraocular pressure response to topical beta-blockers associated with an ADRB2 single-nucleotide polymorphism.

Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jul 2008

McCarty Catherine A, Burmester James K, Mukesh Bickol N, Patchett Richard B, Wilke Russell A

Abstract excerpt

OBJECTIVES: To determine whether candidate pharmacodynamic (beta-adrenergic receptor) and pharmacokinetic (cytochrome P450 2D6) gene polymorphisms are associated with the intraocular pressure (IOP) response to topical beta-blockers. METHODS: Medical records of 18,773 adults in the Personalized Medicine Research Project were searched to extract all IOP measurements for subjects who had been prescribed a topical...

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Source

Identifiers

PMID: 18625943
DOI: 10.1001/archopht.126.7.959

Genes

ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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