Article
Association analysis of beta(2)-adrenergic receptor polymorphisms with hypertension in Japanese.
Hypertension (Dallas, Tex. : 1979) - 1 Feb 2001
Kato N, Sugiyama T, Morita H, Kurihara H, Sato T, Yamori Y, Yazaki Y
Abstract excerpt
Significant evidence has been provided for the pathophysiological involvement of the beta(2)-adrenergic receptor (ADRB2) in hypertension. Among ADRB2 polymorphisms identified to date, 2 amino acid substitutions, Arg16Gly and Gln27Glu, and a promoter variant, T-47C, are considered functionally imp...
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