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Article

Association of Functional ADRB1 (rs1801252) and ADRB2 (rs1042714) Polymorphisms with Primary Open-Angle Glaucoma in a Saudi Cohort.

International journal of molecular sciences - 26 Jul 2026

Kondkar Altaf A, Sultan Tahira, Azad Taif A, Osman Essam A, Almobarak Faisal A, Alsirhy Ehab Y, Al-Obeidan Saleh A

Abstract excerpt

This case-control study investigated the association between β-adrenergic receptors, ADRB1 rs1801252 (A-to-G/Ser49Gly) and ADRB2 rs1042714 (C-to-G/Gln27Glu), polymorphisms and primary open-angle glaucoma (POAG) in a Saudi cohort. Genotyping of 418 participants (167 cases and 251 controls) was performed using real-time PCR assays. Analysis was performed among 412 participants with complete genotype data for both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 42589326
DOI: 10.3390/ijms27156668
PMCID: PMC13466471

Genes

ADRB1
ADRB2

Variants

rs1801252
rs1801252

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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