Article
Evaluation of the beta2-adrenergic receptor gene as a candidate glaucoma gene in 2 ancestral populations.
Archives of ophthalmology (Chicago, Ill. : 1960) - 1 Jan 2007
McLaren Ning, Reed David M, Musch David C, Downs Catherine A, Higashi Misao E, Santiago Cecilia, Radenbaugh Pauline A, Allingham R Rand, Richards Julia E, Moroi Sayoko E
Abstract excerpt
OBJECTIVE: To determine whether the beta(2)-adrenergic receptor (ADRB2) gene is a glaucoma susceptibility locus. DESIGN AND METHODS: The design was an association study stratified by ancestry (white vs black African) and disease (primary open-angle glaucoma vs control subjects). The ADRB2 single nucleotide polymorphisms were determined by sequencing, and the haplotypes of the common single nucleotide...
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