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Article

Beta 2-adrenergic receptor polymorphism and susceptibility to primary congenital and primary open angle glaucoma.

European journal of clinical pharmacology - 1 Oct 2003

Güngör Kivanc, Ozkur Mehtap, Cascorbi Ingolf, Brockmöller Jürgen, Bekir Necdet, Roots Ivar, Aynacioglu A Sükrü

Abstract excerpt

OBJECTIVE: It has been shown that arginine to glycine (Arg16Gly), glutamine to glutamic acid (Gln27Glu) and threonine to isoleucine (Thr164Ile) exchanges in codons 16, 27 and 164, respectively, of the beta 2-adrenergic receptor (B2AR) gene significantly alter receptor function. As B2ARs are located on the afferent blood vessels supplying the ciliary body and trabecular meshwork cells, which control aqueous humour...

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Identifiers

PMID: 13680034
DOI: 10.1007/s00228-003-0658-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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