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6-Thioguanine resistant T-lymphocyte determination as a possible indicator of human ionizing radiation exposure.

Boletin de estudios medicos y biologicos - 1 Jan 2000

Ostrosky-Wegman P, Montero R, Cortinas de Nava C, Hurtado F

Abstract excerpt

We used the autoradiographic assay to assess human in vivo somatic cell gene mutation at the hypoxanthine guanine phosphoribosyl transferase (hgprt) locus in T-lymphocytes. Cells able to incorporate tritiated thymidine in vitro in 6-thioguanine containing short-term cultures were enumerated in order to determine 6-thioguanine resistant (TGr) variant frequencies in cryopreserved lymphocytes from control...

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PMID: 2633789

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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6-Thioguanine resistant T-lymphocyte determination as a possible indicator of human ionizing radiation exposure.PMID 2633789Read ↗

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