Evaluation of the mutagenic effects of SV40 in mouse, hamster, and mouse-human hybrid cells.

doi:10.1007/BF01233058

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Article

Evaluation of the mutagenic effects of SV40 in mouse, hamster, and mouse-human hybrid cells.

Somatic cell and molecular genetics - 1 Jul 1991

Giles R E, Boyce F M, Brockman W W

Abstract excerpt

We have examined the ability of SV40 to induce changes in drug or temperature resistance in mouse, hamster, and mouse-human hybrid cells. SV40 induced a substantial increase of cells resistant to 5-bromodeoxyuridine + trifluorothymidine in Balb/c 3T3 cells and induced an increase of hybrid cells resistant to 6-thioguanine. SV40 was found to be nonmutagenic or weakly mutagenic in other test systems. The 3T3 cells...

Topics

Animals
Antigens, Viral, Tumor
Bromodeoxyuridine
Cell Line, Transformed
Cricetinae
Cricetulus
Drug Resistance
Female
Humans
Hybrid Cells
L Cells
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Inbred BALB C

Mutagenesis

Ovary

Phenotype

Simian virus 40

Temperature

Source

Open in PubMed

Identifiers

PMID: 1653460
DOI: 10.1007/BF01233058

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1653460-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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