Article
Evaluation of the mutagenic effects of SV40 in mouse, hamster, and mouse-human hybrid cells.
Somatic cell and molecular genetics - 1 Jul 1991
Giles R E, Boyce F M, Brockman W W
Abstract excerpt
We have examined the ability of SV40 to induce changes in drug or temperature resistance in mouse, hamster, and mouse-human hybrid cells. SV40 induced a substantial increase of cells resistant to 5-bromodeoxyuridine + trifluorothymidine in Balb/c 3T3 cells and induced an increase of hybrid cells resistant to 6-thioguanine. SV40 was found to be nonmutagenic or weakly mutagenic in other test systems. The 3T3 cells...
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