Article
Controlling the subcellular localization of DNA polymerases iota and eta via interactions with ubiquitin.
The EMBO journal - 21 Jun 2006
Plosky Brian S, Vidal Antonio E, Fernández de Henestrosa Antonio R, McLenigan Mary P, McDonald John P, Mead Samantha, Woodgate Roger
Abstract excerpt
Y-family DNA polymerases have spacious active sites that can accommodate a wide variety of geometric distortions. As a consequence, they are considerably more error-prone than high-fidelity replicases. It is hardly surprising, therefore, that the in vivo activity of these polymerases is tightly r...
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