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Article

Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis.

Proceedings of the National Academy of Sciences of the United States of America - 18 Nov 2008

Acharya Narottam, Yoon Jung-Hoon, Gali Himabindu, Unk Ildiko, Haracska Lajos, Johnson Robert E, Hurwitz Jerard, Prakash Louise, Prakash Satya

Abstract excerpt

Treatment of yeast and human cells with DNA-damaging agents elicits Rad6-Rad18-mediated monoubiquitination of proliferating cell nuclear antigen (PCNA) at its Lys-164 residue [ubiquitin (Ub)-PCNA], and this PCNA modification is indispensable for promoting the access of translesion synthesis (TLS)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19001268
DOI: 10.1073/pnas.0809844105
PMCID: PMC2584706

Genes

PCNA
PIP
UBD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19001268-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Roles of PCNA-binding and ubiquitin-binding domains in human DNA polymerase eta in translesion DNA synthesis.PMID 19001268Read ↗

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