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Article

A novel mechanism of interaction between alpha-synuclein and biological membranes.

Journal of molecular biology - 7 Jul 2006

Kim Yoon Suk, Laurine Emmanuelle, Woods Wendy, Lee Seung-Jae

Abstract excerpt

Conformational abnormalities and aggregation of alpha-synuclein (alpha-syn) have been linked to the pathogenesis of Parkinson's (PD) and related diseases. It has been shown that alpha-syn can stably bind artificial phospholipid vesicles through alpha-helix formation in its N-terminal repeat region. However, little is known about the membrane interaction in cells. In the current study, we determined the...

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Identifiers

PMID: 16762368
DOI: 10.1016/j.jmb.2006.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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