Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mutation analysis of DARPP-32 as a candidate gene for schizophrenia.

Schizophrenia research - 1 Oct 2006

Li Chen-Hao, Liao Hsiao-Mei, Hung Tsai-Wei, Chen Chia-Hsiang

Abstract excerpt

Dopamine- and cAMP-regulated phosphoprotein of relative molecular mass 32kDa (DARPP-32) plays a pivotal role in the signal transduction of several neurotransmitters and neuromodulators that are implicated in the pathophysiology of a variety of neuropsychiatric disorders. A postmortem study reported a significantly reduced DARPP-32 expression in the dorsolateral prefrontal cortex (DLPFC) of patients with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to Cyclic AMP
Share to DNA Fragmentation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Primers

Share to Dopamine and cAMP-Regulated Phosphoprotein 32

Share to Point Mutation

Share to Schizophrenia

Share to Transcriptional Activation

Source

Identifiers

PMID: 16750903
DOI: 10.1016/j.schres.2006.04.003

Genes

AGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mutation analysis of DARPP-32 as a candidate gene for schizophrenia.PMID 16750903Read ↗

Genetic analysis of the gene coding for DARPP-32 (PPP1R1B) in Japanese patients with schizophrenia or bipolar disorder.Semantic proximity Read ↗

An association study between PPP1R1B gene and schizophrenia in the Chinese population.Semantic proximity Read ↗

Effects of the -141C insertion/deletion polymorphism in the dopamine D2 receptor gene on the dopamine system in the striatum in patients with schizophrenia.Semantic proximity Read ↗

Elevated postmortem striatal t-DARPP expression in schizophrenia and associations with DRD2/ANKK1 polymorphism.Semantic proximity Read ↗

BDNF and DARPP-32 genes are not risk factors for schizophrenia in the Malay population.Semantic proximity Read ↗

Reduced prefrontal cortex DARPP-32 mRNA in completed suicide victims with schizophrenia.Semantic proximity Read ↗

Genetic evidence implicating DARPP-32 in human frontostriatal structure, function, and cognition.Semantic proximity Read ↗

Genetic analysis of the DLGAP1 gene as a candidate gene for schizophrenia.Semantic proximity Read ↗

Role of the DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 in schizophrenia.Semantic proximity Read ↗

Genetic and functional analysis of the gene encoding GAP-43 in schizophrenia.Semantic proximity Read ↗

Mutation screening and association study of the beta-adrenergic receptor kinase 2 gene in schizophrenia families.Semantic proximity Read ↗

Advanced research on dopamine signaling to develop drugs for the treatment of mental disorders: Ser311Cys polymorphisms of the dopamine D2-receptor gene and schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.