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Article

Effects of the -141C insertion/deletion polymorphism in the dopamine D2 receptor gene on the dopamine system in the striatum in patients with schizophrenia.

Psychiatry research - 1 Jun 2018

Matsumoto Junya, Nagaoka Atsuko, Kunii Yasuto, Miura Itaru, Hino Mizuki, Niwa Shin-Ichi, Nawa Hiroyuki, Takahashi Hitoshi, Kakita Akiyoshi, Yabe Hirooki

Abstract excerpt

The relationships between -141C insertion/deletion (Ins/Del) polymorphisms in the dopamine D2 receptor gene and the two dopamine system integrators, i.e., dopamine- and cAMP-regulated phosphoprotein of molecular weight 32 kDa (DARPP-32) and calcineurin (CaN), are still unclear. In this study, we assessed the effect of this polymorphism on DARPP-32 and CaN protein expression in the postmortem striatum of patients...

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Identifiers

PMID: 29627696
DOI: 10.1016/j.psychres.2018.03.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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