Article
Role of the DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 in schizophrenia.
PloS one - 1 Jan 2014
Li Jun-Ming, Lu Chao-Lin, Cheng Min-Chih, Luu Sy-Ueng, Hsu Shih-Hsin, Hu Tsung-Ming, Tsai Hsin-Yao, Chen Chia-Hsiang
Abstract excerpt
Aberrant synaptic dysfunction is implicated in the pathogenesis of schizophrenia. The DLGAP2 gene encoding the SAP90/PSD-95-associated protein 2 (SAPAP2) located at the post-synaptic density of neuronal cells is involved in the neuronal synaptic function. This study aimed to investigate whether the DLGAP2 gene is associated with schizophrenia. We resequenced the putative promoter region and all the exons of the...
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