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Article

Mutation screening and association study of the beta-adrenergic receptor kinase 2 gene in schizophrenia families.

Psychiatry research - 15 Feb 2004

Yu Shun-Ying, Takahashi Sakae, Arinami Tadao, Ohkubo Tatsunobu, Nemoto Yasundo, Tanabe Eiichi, Fukura Yoichi, Matsuura Masato, Han Yong-Hua, Zhou Ru-Len, Shen Yu-Cun, Matsushima Eisuke, Kojima Takuya

Abstract excerpt

Chromosome 22q12 is one of the most promising regions for harboring a risk gene for schizophrenia. We have reported significant linkage of intermediate phenotypes for schizophrenia with markers within or near the beta-adrenergic receptor kinase 2 (ADRBK2, or GRK3) gene, which is highly expressed in dopaminergic pathways in the central nervous system, and mediates homologous desensitization for a variety of...

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Source

Identifiers

PMID: 15006433
DOI: 10.1016/j.psychres.2003.12.003

Genes

GRK3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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