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An association study between PPP1R1B gene and schizophrenia in the Chinese population.

Progress in neuro-psychopharmacology & biological psychiatry - 15 Aug 2007

Hu Jian-Xin, Yu Lan, Shi Yong-Yong, Zhao Xin-Zhi, Meng Jun-Wei, He Guang, Xu Yi-Feng, Feng Guo-Yin, He Lin

Abstract excerpt

Schizophrenia has been linked with dysfunctions of glutamatergic, dopaminergic, and serotonergic neurotransmission. Dopamine- and cAMP-regulated phosphoprotein of relative molecular mass 32 kDa (DARPP-32), encoded by PPP1R1B (protein phosphatase 1, regulatory/inhibitor subunit 1B) gene, is enriched in neostriatal medium spiny neurons. It plays a key regulator role in dopaminergic and glutamatergic signaling...

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Identifiers

PMID: 17618027
DOI: 10.1016/j.pnpbp.2007.05.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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