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Article

Reduced prefrontal cortex DARPP-32 mRNA in completed suicide victims with schizophrenia.

Schizophrenia research - 1 Aug 2008

Feldcamp Laura A, Souza Renan P, Romano-Silva Marco, Kennedy James L, Wong Albert H C

Abstract excerpt

Dopamine-and-cAMP-regulated neuronal phosphoprotein (32 kDa) (DARPP-32), encoded by PPP1R1B, is expressed in brain regions receiving dopaminergic projections, including the prefrontal cortex (PFC), and is implicated in the pathophysiology of schizophrenia. The broad functional capacity of DARPP-32 has potential relevance to both psychotic and negative symptoms of schizophrenia. We wished to determine if DARPP-32...

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Identifiers

PMID: 18573638
DOI: 10.1016/j.schres.2008.05.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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