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Genetic and functional analysis of the gene encoding GAP-43 in schizophrenia.

Schizophrenia research - 1 Feb 2012

Shen Yu-Chih, Tsai Ho-Min, Cheng Min-Chih, Hsu Shih-Hsin, Chen Shih-Fen, Chen Chia-Hsiang

Abstract excerpt

OBJECTIVES: In earlier reports, growth-associated protein 43 (GAP-43) has been shown to be critical for initial establishment or reorganization of synaptic connections, a process thought to be disrupted in schizophrenia. Additionally, abnormal GAP-43 expression in different brain regions has been linked to this disorder in postmortem brain studies. In this study, we investigated the involvement of the gene...

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PMID: 22138049
DOI: 10.1016/j.schres.2011.11.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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