Article
Genome scanning by two-dimensional DNA typing: the use of repetitive DNA sequences for rapid mapping of genetic traits.
Electrophoresis - 1 Jan 2000
Uitterlinden A G, Slagboom E P, Mullaart E, Meulenbelt I, Vijg J
Abstract excerpt
The existence of repetitive DNA sequences offers the possibility to assess the mammalian genome for individual variation in its entirety rather than at one or only a few sites. In order to fully explore the various sets of mammalian repeat sequences for this purpose, analytical tools are required which allow many if not all individual members of sets of repetitive elements to be resolved and identified in terms...
Topics
- Alleles
- Base Sequence
- Cosmids
- DNA
- DNA Probes
- Electrophoresis, Gel, Two-Dimensional
- Female
- Genetic Markers
- Humans
- Male
- Molecular Sequence Data
- Pedigree
