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Article

Two-dimensional electrophoresis southern transfer method for detecting human genome variability using a LINE-1 sequence probe.

Analytical biochemistry - 20 May 1995

Nakashima H, Yi M, Ichikawa N, LeBlond G F, Antonarakis S E, Ts'o P O

Abstract excerpt

A "high-resolution, two-dimensional Southern transfer" method has been developed and was used to examine the distribution of a class of interspersed repeated sequences in human genomes. This method consists of two separate restriction enzyme digestions, including an in situ digestion, and two-dimensional electrophoresis using a large-sized agarose gel. The first 163-base-pair region of the human LINE-1...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 7573953
DOI: 10.1006/abio.1995.1287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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