Restriction landmark genome scanning for the detection of mutations.

doi:10.1007/978-1-59745-548-0_10

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Article

Restriction landmark genome scanning for the detection of mutations.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2008

Asakawa Jun-ichi

Abstract excerpt

There is a continuing need for more efficient methods to examine mutations in humans and other species resulting from exposures to environmental toxins and radiation. Environmental genomic studies, which often utilize nonmodel system species and as a result, there is a particular need for a method that does not rely on the availability of genome sequence information. Restriction landmark genome scanning (RLGS) is...

Topics

Animals
DNA
DNA Mutational Analysis
DNA Restriction Enzymes
Electrophoresis, Gel, Two-Dimensional
Genome
Genomics
Humans
Mutation
Restriction Mapping

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PMID: 18642600
DOI: 10.1007/978-1-59745-548-0_10

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