Article
Quantitative and qualitative genetic variation in two-dimensional DNA gels of human lymphocytoid cell lines.
Electrophoresis - 1 Feb 1995
Asakawa J, Kuick R, Neel J V, Kodaira M, Satoh C, Hanash S M
Abstract excerpt
There is a continuing need for more efficient methods to examine human (and other) populations for altered germinal and somatic cell mutation rates. To this end, we have explored the potential usefulness of two-dimensional (2-D) electrophoresis of human DNA fragments obtained from restriction-enz...
Topics
- Autoradiography
- Base Sequence
- Cell Line
- DNA
- DNA Mutational Analysis
- Electrophoresis, Agar Gel
- Female
- Genetic Variation
- Humans
- Lymphocytes
- Male
- Molecular Sequence Data
- Mutation
- Polymorphism, Restriction Fragment Length