Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Restriction landmark genomic scanning method and its various applications.

Electrophoresis - 1 Apr 1993

Hayashizaki Y, Hirotsune S, Okazaki Y, Hatada I, Shibata H, Kawai J, Hirose K, Watanabe S, Fushiki S, Wada S

Abstract excerpt

We have developed a new genome scanning method (restriction landmark genomic scanning (RLGS), based on the new concept of using restriction enzyme sites as landmarks. RLGS employs direct end labeling of the genomic DNA digested with a restriction enzyme and two-dimensional electrophoresis with high-resolution. Its advantages are: (i) high-speed scanning ability, allowing simultaneous scanning of thousands of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Binding Sites
Share to DNA
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Amplification

Share to Gene Deletion

Share to Methylation

Share to Mutation

Source

Identifiers

PMID: 8388788
DOI: 10.1002/elps.1150140145

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Restriction landmark genomic scanning method and its various applications.PMID 8388788Read ↗

Restriction landmark genome scanning for the detection of mutations.Semantic proximity Read ↗

High-speed positional cloning based on restriction landmark genome scanning.Semantic proximity Read ↗

[Development in ligase-mediated techniques for bio-molecular analysis].Semantic proximity Read ↗

Genetic profile of the SMXA recombinant inbred mouse strains revealed with restriction landmark genomic scanning.Semantic proximity Read ↗

Marking of specific sequences in double-stranded DNA molecules--SNP detection and direct observation.Semantic proximity Read ↗

Genome scanning by two-dimensional DNA typing: the use of repetitive DNA sequences for rapid mapping of genetic traits.Semantic proximity Read ↗

The use of restriction landmark genomic scanning to scan the mouse genome for endogenous loci with imprinted patterns of methylation.Semantic proximity Read ↗

Intratumoral genomic heterogeneity in human hepatocellular carcinoma detected by restriction landmark genomic scanning.Semantic proximity Read ↗

Chlorophyll-deficient mutants of rice demonstrated the deletion of a DNA fragment by heavy-ion irradiation.Semantic proximity Read ↗

A genome scanning approach to assess the genetic effects of radiation in mice and humans.Semantic proximity Read ↗

Genetic variation detected by quantitative analysis of end-labeled genomic DNA fragments.Semantic proximity Read ↗

Genomic DNA analyses of spontaneous hepatocellular carcinomas in LEC rat liver using a new technique.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.