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Article

Two-dimensional DNA typing of human pedigrees: spot pattern characterization and segregation.

Genomics - 10 Oct 1995

Mullaart E, Verwest A M, Børglum A D, Uitterlinden A G, te Meerman G J, Kruse T A, Vijg J

Abstract excerpt

By two-dimensional (2-D) genome typing, i.e., electrophoretic separation of restriction enzyme-digested genomic DNA on the basis of both size and sequence in denaturing gradient gels followed by hybridization analysis, several hundred alleles (spots) can be analyzed in parallel, using a micro- or minisatellite core probe. We studied the segregation of 213 and 214 spots detected by microsatellite core probe (CAC)n...

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Identifiers

PMID: 8575756
DOI: 10.1006/geno.1995.9955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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