Identification of complex DNA polymorphisms based on variable number of tandem repeats (VNTR) and restriction site polymorphism.

Abstract excerpt

Restriction fragment length polymorphisms (RFLPs) of genomic DNA are generally attributable to base changes that create or abolish restriction endonuclease sites or to nucleotide sequence insertions or deletions that alter the distance separating two restriction sites. Minisatellite or variable number of tandem repeats (VNTR) markers are prominent examples of the latter type of polymorphism. In this report, we...

Topics

• Alleles
• Blotting, Southern
• DNA
• DNA Probes
• Humans
• Phenotype
• Polymorphism, Restriction Fragment Length
• Repetitive Sequences, Nucleic Acid
• Restriction Mapping