Article
One-dimensional genome scanning: identification of the basis of a mouse mutation and identification of genomic changes in ovarian carcinoma.
Electrophoresis - 1 Feb 1995
Brilliant M H, Gondo Y, Magliocco A
Abstract excerpt
We have developed a simple one-dimensional electrophoretic method, genome scanning, that can be used to identify large-scale genomic differences between two or more DNA samples. Genome scanning is especially useful in the detection of genetic amplifications, deletions, and rearrangements. The ass...
Topics
- Animals
- Blotting, Southern
- DNA
- DNA Mutational Analysis
- DNA Probes
- DNA, Neoplasm
- Electrophoresis, Agar Gel
- Female
- Genes, Intracisternal A-Particle
- Genetic Techniques
- Genome
- Humans
- Male
- Mice
- Mice, Inbred C57BL
- Mutation
- Ovarian Neoplasms
- Retroviridae