Article
Two-dimensional gene scanning: exploring human genetic variability.
Electrophoresis - 1 Jun 1999
Vijg J, van Orsouw N J
Abstract excerpt
Current methods for mutation detection are not optimized for the generation of highly accurate data on multiple genes of hundreds of individuals in population-based studies. Two-dimensional gene scanning (TDGS) is a high-resolution system for detecting mutational variants in multiple genes in parallel. TDGS is based on a combination of extensive multiplex polymerase chain reaction (PCR) and two-dimensional (2-D)...
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