Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular genetic studies in medulloblastomas: evidence for tumor suppressor genes at the chromosomal regions 1q31-32 and 17p13.

Klinische Padiatrie - 1 Jan 2000

Pietsch T, Koch A, Wiestler O D

Abstract excerpt

BACKGROUND: Medulloblastoma represents a common primitive neuroectodermal tumor of the cerebellum, the molecular pathogenesis of which has not been identified. Previous cytogenetic observations disclosed aberrations of chromosome 1 and 17 in medulloblastomas. In the present study, we have molecularly characterized the affected chromosomal segments. PATIENTS AND METHODS: A panel of microsatellites on chromosomes 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Alleles
Share to Child

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Child, Preschool

Share to Chromosome Deletion

Share to Chromosome Mapping

Share to Genes, Tumor Suppressor

Share to Microsatellite Repeats

Source

Identifiers

PMID: 9293446
DOI: 10.1055/s-2008-1043965

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular genetic studies in medulloblastomas: evidence for tumor suppressor genes at the chromosomal regions 1q31-32 and 17p13.PMID 9293446Read ↗

Cytogenetics and molecular genetics of childhood brain tumors.Semantic proximity Read ↗

Molecular analysis of chromosome 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors.Semantic proximity Read ↗

Involvement of multiple chromosome 17p loci in medulloblastoma tumorigenesis.Semantic proximity Read ↗

Isochromosome 17q Is a Negative Prognostic Factor in Poor-Risk Childhood Medulloblastoma PatientsSemantic proximity Read ↗

Identification of a consistent region of allelic loss on 1p32 in meningiomas: correlation with increased morbidity.Semantic proximity Read ↗

Loss of heterozygosity on 6q, 16q, and 17p in human central nervous system primitive neuroectodermal tumors.Semantic proximity Read ↗

Pediatric brain tumors: loss of heterozygosity at 17p and TP53 gene mutations.Semantic proximity Read ↗

Identification of two distinct deleted regions on the short arm of chromosome 1 and rare mutation of the CDKN2C gene from 1p32 in oligodendroglial tumors.Semantic proximity Read ↗

Recurrent 1;17 translocations in human neuroblastoma reveal nonhomologous mitotic recombination during the S/G2 phase as a novel mechanism for loss of heterozygosity.Semantic proximity Read ↗

Prognostic implications of chromosome 17p deletions in human medulloblastomasSemantic proximity Read ↗

[Genome-wide genetic study of medulloblastoma using allelotype analysis].Semantic proximity Read ↗

Lissencephaly. A human brain malformation associated with deletion of the LIS1 gene located at chromosome 17p13Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.