Article
Chromosome arm 17p deletion analysis reveals molecular genetic heterogeneity in supratentorial and infratentorial primitive neuroectodermal tumors of the central nervous system.
Cancer genetics and cytogenetics - 1 Aug 1997
Burnett M E, White E C, Sih S, von Haken M S, Cogen P H
Abstract excerpt
The current World Health Organization (WHO) classification groups together both infratentorial neoplasms (medulloblastomas) and their supratentorial counterparts as primitive neuroectodermal tumors (PNETs), implying a common origin. Previous analyses of medulloblastoma have shown loss of chromoso...
Topics
- Adolescent
- Brain Neoplasms
- Cerebellar Neoplasms
- Child
- Child, Preschool
- Chromosome Deletion
- Chromosomes, Human, Pair 17
- Female
- Genes, p53
- Genetic Heterogeneity
- Humans
- Infant
- Infant, Newborn
- Male
- Medulloblastoma
- Microsatellite Repeats
- Mutation
- Polymerase Chain Reaction