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Article

Alterations at chromosome 17 loci in peripheral nerve sheath tumors.

Journal of neuropathology and experimental neurology - 1 Jan 1995

Lothe R A, Slettan A, Saeter G, Brøgger A, Børresen A L, Nesland J M

Abstract excerpt

Little is known about the molecular genetic changes in malignant peripheral nerve sheath tumors (MPNST). Inactivation of the TP53 gene in 17p has been reported in a few tumors. The MPNST is one of the manifestations of neurofibromatosis 1 (NF1), suggesting that the NF1 gene in 17q might be important. We present a study of 15 neurofibromas and MPNST from nine individuals. Seven patients had NF1, and six of these...

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Identifiers

PMID: 7815081
DOI: 10.1097/00005072-199501000-00008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Alterations at chromosome 17 loci in peripheral nerve sheath tumors.PMID 7815081Read ↗

Frequent genomic imbalances in chromosomes 17, 19, and 22q in peripheral nerve sheath tumours detected by comparative genomic hybridization analysisSemantic proximity Read ↗

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Differential<i>NF1</i>,<i>p16</i>, and<i>EGFR</i>Patterns by Interphase Cytogenetics (FISH) in Malignant Peripheral Nerve Sheath Tumor (MPNST) and Morphologically Similar Spindle Cell NeoplasmsSemantic proximity Read ↗

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