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Article

Activation-induced cytidine deaminase acts on double-strand breaks in vitro.

Molecular immunology - 1 Feb 2007

Shen Hong Ming

Abstract excerpt

Activation-induced cytidine deaminase (AID) is likely responsible for DNA cytidine deamination, although it may also act as an RNA deaminase. It functions on single-stranded DNA, the non-template strand in double-stranded DNA during transcription, or both strands in supercoiled DNA. To ask whether AID is able to deaminate cytidine at DNA breaks, plasmids, containing a SnaBI site (TAC downward arrowGTA) that forms...

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Identifiers

PMID: 16697045
DOI: 10.1016/j.molimm.2006.03.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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