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Article

Mutator effects and mutation signatures of editing deaminases produced in bacteria and yeast.

Biochemistry. Biokhimiia - 1 Jan 2011

Lada A G, Krick C Frahm, Kozmin S G, Mayorov V I, Karpova T S, Rogozin I B, Pavlov Y I

Abstract excerpt

Enzymatic deamination of bases in DNA or RNA leads to an alteration of flow of genetic information. Adenosine deaminases edit RNA (ADARs, TADs). Specialized cytidine deaminases are involved in RNA/DNA editing in lipid metabolism (APOBEC1) and in innate (APOBEC3 family) and humoral (AID) immunity. APOBEC2 is required for proper muscle development and, along with AID, was implicated in demethylation of DNA. The...

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Source

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Identifiers

PMID: 21568845
DOI: 10.1134/s0006297911010135
PMCID: PMC3906858

Genes

APOBEC2
APOBEC1
APOBEC4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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