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Article

The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation.

PLoS genetics - 1 May 2006

Kalantry Sundeep, Magnuson Terry

Abstract excerpt

The Polycomb group (PcG) proteins are thought to silence gene expression by modifying chromatin. The Polycomb repressive complex 2 (PRC2) plays an essential role in mammalian X-chromosome inactivation (XCI), a model system to investigate heritable gene silencing. In the mouse, two different forms...

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Source

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Identifiers

PMID: 16680199
DOI: 10.1371/journal.pgen.0020066
PMCID: PMC1456320

Genes

EED

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16680199-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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The Polycomb group protein EED is dispensable for the initiation of random X-chromosome inactivation.PMID 16680199Read ↗

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Differences between homologous alleles of olfactory receptor genes require the Polycomb Group protein Eed.Semantic proximity Read ↗

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Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms.Semantic proximity Read ↗

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