Article
Cellular memory of transcriptional states by Polycomb-group proteins.
Seminars in cell & developmental biology - 1 Apr 1999
Jacobs J J, van Lohuizen M
Abstract excerpt
The Polycomb-group constitutes an important, widely conserved group of transcriptional repressors best known for their function in stably maintaining the inactive expression patterns of key developmental regulators, including homeotic genes. Together with the counteracting trithorax-group proteins, they establish a form of cellular memory by faithfully maintaining transcription states determined early in...
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