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Article

Striatal dopamine transporter binding in Parkinson's disease associated with the LRRK2 Gly2019Ser mutation.

Movement disorders : official journal of the Movement Disorder Society - 1 Aug 2006

Isaias Ioannis U, Benti Riccardo, Goldwurm Stefano, Zini Michela, Cilia Roberto, Gerundini Paolo, Di Fonzo Alessio, Bonifati Vincenzo, Pezzoli Gianni, Antonini Angelo

Abstract excerpt

We measured striatal dopamine transporter binding using [(123)I]ioflupane and SPECT in patients with Parkinson's disease associated with the LRRK2 (PARK8) Gly2019Ser gene mutation (LRRK2-PD) and in gene-negative patients with idiopathic Parkinson's disease (IPD) of comparable disease duration and severity. The LRRK2-PD group consisted of a total of 10 patients (3 sporadic) with mean age 62 +/- 14 years, disease...

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Identifiers

PMID: 16671078
DOI: 10.1002/mds.20909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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