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Article

DAT imaging and clinical biomarkers in relatives at genetic risk for LRRK2 R1441G Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Mar 2016

Bergareche Alberto, Rodríguez-Oroz Maria Cruz, Estanga Ainara, Gorostidi Ana, López de Munain Adolfo, Castillo-Triviño Tamara, Ruiz-Martínez Javier, Mondragón Elisabet, Gaig Carles, Lomeña Francisco, Sarasqueta Cristina, Tolosa Eduardo, Martí-Massó José Félix

Abstract excerpt

BACKGROUND: The objective of this study was to study motor and nonmotor symptoms and striatal dopaminergic denervation, as well as the relationship between them, in a cohort of asymptomatic relatives of patients with Parkinson's disease (PD) with the R1441G-leucine-rich repeat kinase 2 mutation. METHODS: Asymptomatic relatives of patients with PD and this mutation were tested for the presence of the mutation and...

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PMID: 26686514
DOI: 10.1002/mds.26478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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