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Article

Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism.

Brain : a journal of neurology - 1 Jun 2004

Scherfler Christoph, Khan Naheed L, Pavese Nicola, Eunson Louise, Graham Elizabeth, Lees Andrew J, Quinn Niall P, Wood Nicholas W, Brooks David J, Piccini Paola P

Abstract excerpt

To investigate striatal and cortical pre- and postsynaptic dopaminergic function in parkin-linked parkinsonism, 13 unrelated patients homozygous or compound heterozygous for parkin mutations were studied with [(18)F]dopa and [(11)C]raclopride (RAC) PET. Data were compared with a young-onset Parki...

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Source

Identifiers

PMID: 15090472
DOI: 10.1093/brain/awh150

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15090472-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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