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Article

Nuclear localization in the biology of the CD40 receptor in normal and neoplastic human B lymphocytes.

The Journal of biological chemistry - 7 Jul 2006

Lin-Lee Yen-Chiu, Pham Lan V, Tamayo Archito T, Fu Lingchen, Zhou Hai-Jun, Yoshimura Linda C, Decker Glenn L, Ford Richard J

Abstract excerpt

CD40 is a tumor necrosis factor (TNF) receptor superfamily, (TNFR; TNFRSF-5) member, that initiates important signaling pathways mediating cell growth, survival, and differentiation in B-lymphocytes. Although CD40 has been extensively studied as a plasma membrane-associated growth factor receptor, we demonstrate here that CD40 is present not only in the plasma membrane and cytoplasm but also in the nucleus of...

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Share to B-Lymphocytes
Share to CD40 Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Green Fluorescent Proteins

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Share to Microscopy, Confocal

Share to Protein Transport

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Source

Identifiers

PMID: 16644731
DOI: 10.1074/jbc.M513315200

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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