Article
Signaling and protein associations of a cell permeable CD40 complex in B cells.
Molecular immunology - 1 Jan 2004
Zoog Stephen J, Papov Vladimir V, Pullen Steven S, Jakes Scott, Kehry Marilyn R
Abstract excerpt
Signaling through the CD40 receptor activates diverse molecular pathways in a variety of immune cell types. To study CD40 signaling complexes in B cells, we produced soluble CD40 cytoplasmic domain multimers that translocate across cell membranes and engage intracellular CD40 signaling pathways. As visualized by fluorescence microscopy, rapid transduction of recombinant Antennapedia-isoleucine zipper (Izip)-CD40...
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