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Article

Molecular characterization of CD40 signaling intermediates.

The Journal of biological chemistry - 16 Nov 2001

Werneburg B G, Zoog S J, Dang T T, Kehry M R, Crute J J

Abstract excerpt

Signal transduction through the CD40 receptor is initiated by binding of its trimeric ligand and propagated by interactions of tumor necrosis factor receptor-associated factor (TRAF) proteins with the multimerized CD40 cytoplasmic domain. Using defined multimeric constructs of the CD40 cytoplasmic domain expressed as either soluble or myristoylated proteins, we have addressed the extent of receptor...

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Share to CD40 Antigens
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11562359
DOI: 10.1074/jbc.M104994200

Genes

TRAF1
TRAF2
TRAF3
TRAF5
TRAF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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