Article

BCL3 encodes a nuclear protein which can alter the subcellular location of NF-kappa B proteins.

1994-06-01

Abstract excerpt

BCL3 is a candidate proto-oncogene involved in the recurring translocation t(14;19) found in some patients with chronic lymphocytic leukemia. BCL3 protein acts as an I kappa B in that it can specifically inhibit the DNA binding of NF-kappa B factors. Here, we demonstrate that BCL3 is predominantly a nuclear protein and provide evidence that its N terminus is necessary to direct the protein into the nucleus. In con...

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Identifiers and source

Literature Corpus work: 06f0c97f-730d-5446-9ac8-768bf9a5841a
DOI: 10.1128/mcb.14.6.3915

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