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Article

CD40 Ligand in CLL Pathogenesis and Therapy

1 Jan 2000

Abstract excerpt

Advances in immunology during the past three decades have facilitated our understanding of the biology of specific lymphoid neoplasms including chronic lymphocytic leukemia (CLL). Investigations in our laboratory have focused on CD40, a critical regulator of B cell survival and differentiation, and its ligand, CD154 (CD40L). We have established that in some cases of CLL the malignant cells express both CD40 and...

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Identifiers

PMID: 11042507
DOI: 10.3109/10428190009058499

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Source receipt: pubmed, retrieved 7 Sept 2026.

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