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Article

Cigarette smoking strongly modifies the association of LOC387715 and age-related macular degeneration.

American journal of human genetics - 1 May 2006

Schmidt Silke, Hauser Michael A, Scott William K, Postel Eric A, Agarwal Anita, Gallins Paul, Wong Frank, Chen Yu Sarah, Spencer Kylee, Schnetz-Boutaud Nathalie, Haines Jonathan L, Pericak-Vance Margaret A

Abstract excerpt

We used iterative association mapping to identify a susceptibility gene for age-related macular degeneration (AMD) on chromosome 10q26, which is one of the most consistently implicated linkage regions for this disorder. We employed linkage analysis methods, followed by family-based and case-control association analyses, using two independent data sets. To identify statistically the most likely AMD-susceptibility...

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Share to Chromosomes, Human, Pair 10
Share to Complement Factor H

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Homozygote

Share to Macular Degeneration

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Source

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Identifiers

PMID: 16642439
DOI: 10.1086/503822
PMCID: PMC1474047

Genes

CFH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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