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Article

Association of CFH Y402H and LOC387715 A69S with progression of age-related macular degeneration.

JAMA - 25 Apr 2007

Seddon Johanna M, Francis Peter J, George Sarah, Schultz Dennis W, Rosner Bernard, Klein Michael L

Abstract excerpt

CONTEXT: Studies have reported that single-nucleotide polymorphisms in the genes CFH and LOC387715 are associated with age-related macular degeneration (AMD). OBJECTIVE: To assess whether these genetic variants have prognostic importance for progression to advanced AMD and related visual loss. DESIGN, SETTING, AND PARTICIPANTS: Prospective analysis of 1466 white participants in the Age-Related Eye Disease Study...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17456821
DOI: 10.1001/jama.297.16.1793

Genes

CFH

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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